2010-01-22
The Institute of Physical-Chemical Medicine of Moscow and Vector introduced sequences today from 10 samples into GenBank with the HA and NA segments. The 9 samples that are dated were taken in November 2009 and perhaps are representative of ΣPF11 at that stage in Russia. 60% of those sequences fall onto the cross-linked background with HA syn413K and NA syn407V.
Tomsk08 from lung tissue is a 225G case, presumably fatal, with 131P and Russia100 carries 225N with 131P. Russia61 is TamiFlu Resistant in typical fashion with NA 275Y. None of the three falls on the cross linked background.
Cross Linkage Sequences
Kurgan01 with HA 214E and NA mixture at 407
Russia4 with HA syn238E and 324I
Russia12 with HA 324I
Russia19 with HA 324I
Russia171 with HA 165N
Russia180 with HA 165N, syn239P and 264G
This viral reservoir appears to be far from stable in this particular geography and neighboring areas.
hat-tip sharon sanders
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