Saturday, June 4, 2011
Researchers with the Beijing Genomics Institute, the world's largest DNA sequencing center, have found genes in the newly identified 0104 strain of E. Coli bacteria that made it resistant to major classes of antibiotics including sulfonamide, cephalothin, penicillin and streptomycin.
This helped explain why doctors in Europe had difficulties in fighting the bug that has killed 18 people and sickened nearly 2,000, BGI's major research arm in Shenzhen said on its website Saturday.
This would help doctors choose right medicines for the treatment, it said.
The researchers are developing a diagnostic kit which will be used to detect the bacteria and prevent the epidemic from spreading further.
The Chinese researchers obtained DNA samples of the bacteria from collaborating scientists in Germany and fully sequenced its genome in three days this week.
They announced on Thursday the E. Coli spreading through Europe was "a new strain of bacteria that is highly infectious and toxic".
The 0104 strain of E. Coli was not previously involved in any E. Coli outbreaks. However, it has 93 percent sequence similarity with the EAEC 55989 E. Coli strain which was isolated in the Central African Republic and known to cause seriously diarrhea, BGI said.
The source of the outbreak is unknown, but scientists say it is highly likely to have originated in contaminated vegetables or salad in Germany.
Jun 4, 2011 11:17 AM By Sapa-dpa
Conflicting theories on the origins of the E coli outbreak, which has killed 18 people in Germany so far, emerged in the country's media on Saturday.
A restaurant in the northern coastal city of Luebeck, near Hamburg, was probed by health experts after 17 people who had eaten there became infected with the virulent strain known as enterohaemorrhagic Escherichia coli (EHEC), the regional daily Luebecker Nachrichten reported.
However, Focus magazine reported the origin could lie in an anniversary celebration for the port of Hamburg at the beginning of May. The celebrations drew around 1.5 million visitors over the period May 6-8.
Both reports were based on information that experts from the Berlin-based Robert Koch Institute, which is responsible for disease control and prevention and falls under the federal Health Ministry, had probed the conflicting theories.
The institute could not be reached on Saturday for confirmation.
The national daily Sueddeutsche Zeitung earlier reported in its online edition that 34 women from a trade union organization had met in Luebeck May 12-14 and that at least had eight come down with the EHEC bug, one of whom had died.
A Hamburg hospital admitted the first cases suffering from EHEC in mid-May. The outbreak has since claimed at least 19 lives in Europe.
Initial theories that the bug originated in Spanish cucumbers or in fresh produce from the Netherlands have largely been discounted.
German health authorities are advising against the consumption of raw cucumbers, tomatoes and lettuce. Vegetable growers and traders have had to discard large quantities of produce and suffered serious economic consequences.
The World Health Organization reported that by Thursday, 1,122 cases of EHEC had been reported, with 502 cases of haemolytic-uraemic syndrome (HUS), a form of kidney failure caused by this E coli strain, resulting.
Eleven European countries and the United States had all notified cases, the WHO said.
German health authorities scrambling to find the source of a deadly E. coli outbreak are zeroing in on a restaurant in Lübeck. According to a media report, 17 people sick from the bacteria ate there between May 12 and 14.
Staff from Germany's national disease centre, the Robert Koch Institute (RKI), were investigating the situation in Lübeck.
"The restaurant is not at fault, but the supply chain can potentially provide the crucial clue on how the pathogen came into circulation," Werner Solbach, a microbiologist at the university hospital in Lübeck told daily Lübecker Nachrichten.
The paper reported Saturday that a group of Danish visitors ate at the restaurant for lunch. Later on, eight participants fell ill.
During the same period, another group in town for a seminar also ate at the restaurant. The 30 women were members of the Deutsche Steuer-Gewerkschaft tax union and hailed from around Germany.
"So far, we know of eight cases, some of them very serious," Dieter Ondracek, the union's chairman in Berlin, told the paper.
"One woman from North Rhine-Westphalia has died."
Responding to a query from news agency DAPD, a spokesman for the Kiel health ministry confirmed that participants of the seminar had fallen ill following a visit to Lübeck.
Solbach told Lübecker Nachrichten that another serious case appeared to be linked to the restaurant. A child from southern Germany became ill after visiting the restaurant for a family gathering during the same time period.
Friday, June 3, 2011
Doctors treating the world’s deadliest E. coli outbreak have little beyond water and dialysis machines to help them clear the infection from patients, according to infectious disease specialists.
The new strain of E. coli, which has killed at least 18 people in Europe, produces a poisonous bi-product called shiga toxin that damages the kidneys of some patients and requires the use of dialysis to scrub the blood clean. Some patients need transfusions after the bacteria dissolve their red blood cells, said Robert Tauxe, deputy director of food-borne illness at the U.S. Centers for Disease Control and Prevention.
Germany, alone, has reported 520 cases of the kidney ailment. Overall, 1,823 cases of E. coli infection have been confirmed, according to the World Health Organization in Geneva. In less severe cases, doctors use fluids to maintain hydration and stream the diarrhea-causing toxins through the body. Antibiotics don’t help, and can worsen the illness.
“It’s clearly a more severe disease than is normally seen because of this kidney failure association,” said Stephen Calderwood, chief of the infectious disease division at Massachusetts General Hospital in Boston. “There is some data if you keep the patient hydrated it may lessen the kidney disease. What is recommended is supportive treatment -- no antibiotics but maintain hydration.”
Antibiotics can’t be used because they increase the release of toxins into the bloodstream, compounding kidney damage, Calderwood said. The one class of antibiotics that doesn’t do this, known as carbapenems, is unlikely to help with E. coli, though they may be useful for patients who are simultaneously fighting additional infections, he said.
The new E. coli strain, previously identified in isolated cases but never linked to an outbreak, begins with symptoms similar to more common types of the bacteria. Diarrhea starts anywhere from two to seven days after eating tainted foods, though most cases occur in the three to four-day range.
Diarrhea often contains blood and can be accompanied by fever, abdominal cramps and vomiting, Claudia Stein, director of health information, evidence and research at the WHO, said in a telephone interview.
“It makes your guts bleed; the bloody diarrhea is really a hallmark,” Stein said. “Somebody with bloody diarrhea should not wait. Go straight to their medical practitioner and report this, and then they have to be hospitalized.”
At the hospital, patients will be given fluids to begin the cleansing process, intravenously if necessary, she said.
All humans and animals carry E. coli in their intestines, and those strains are usually harmless, according to the Stockholm-based European Centre for Disease Prevention and Control. Some variants cling to the walls of the intestines and produce toxins that cause illnesses ranging from diarrhea and nausea to the potentially fatal kidney complication, known as hemolytic uremic syndrome, or HUS.
In addition to the 520 German cases of the kidney illness linked to the spread of E-coli, another 30 have been reported in Sweden, Spain, Denmark, the U.K. and the Netherlands, said the European Centre for Disease Prevention and Control. Seventeen people in Germany and one in Sweden have died, the WHO and European disease agency have reported....
WHO warns against hasty antibiotic use for E. coli
Friday, June 3, 2011 8:28 am
GENEVA (AP) — The World Health Organization has cautioned people against taking antibiotics if sickened by the E. coli outbreak that began in Germany last month.
The U.N. health agency says anti-diarrhea medication also isn't recommended as it stops the bacteria from quickly leaving the body.
WHO epidemiologist Andrea Ellis says use of either treatment "can actually make the situation worse."
But she told reporters in Geneva on Friday that doctors treating infected patients can prescribe such drugs in certain specific cases.
WHO has no active role in combating the outbreak that has so far sickened over 1,700 people, mostly in Germany, and killed 18.
By MIKE STOBBE, AP Medical Writer – 2 hours ago
ATLANTA (AP) — Four people in the U.S. were apparently sickened by the food poisoning outbreak in Europe, health officials said Friday. Three are hospitalized with a serious complication.
All four were in northern Germany in May. Though they didn't stay at the same hotel or eat at the same restaurants, officials are confident that they were infected with E. coli in that country.
Three of them — two women and a man — are hospitalized with kidney failure, a complication of E. coli that has become a hallmark of the outbreak. One of the four fell ill while on a plane to the U.S.
Two other cases are being investigated in U.S. service members in Germany, said Dr. Chris Braden, of the Centers for Disease Control and Prevention.
The source of the outbreak hasn't been pinpointed but the focus has been on fresh tomatoes, lettuce and cucumbers. More than 1,800 people have fallen ill, nearly all in Germany.
In a teleconference Friday with reporters, a Food and Drug Administration official said produce in the U.S. remains safe. The government has stepped up testing of food from Germany and Spain, but very little is imported from those countries or the rest of Europe.
The United States has "one of the safest food supplies in the world," said Don Kraemer, deputy director of the FDA's Center for Food Safety and Applied Nutrition.
Few details about the four ill people in the U.S. have been released..
Jun 4, 2011
PARIS - THE deadly kidney disease reported in a quarter of the recent E. coli cases in Germany and 11 other nations is the worst ever outbreak of haemolytic uraemic syndrome (HUS), a top expert said on Friday.
'This is the largest epidemic of HUS to have occurred anywhere in the world,' said Dr Francois-Xavier Weill, head of France's National Reference Centre for Escherichia coli (E. coli).
More than 550 cases of the kidney-wrecking condition have been reported since the outbreak in northern Germany of a virulent strain of enterohaemorrhagic E. coli (EHEC), according to the European Centre for Disease Prevention and Control.
Twelve of these HUS cases - eleven in Germany and one in Sweden - have proven fatal as of midday on Friday, the ECDC said.
More than 2,000 people are known to have been infected by the rogue bacteria, whose origins continue to elude German and international health officials.
'Until we have discovered exactly what food stuff is responsible and withdrawn it, there will be new cases. Finding it is the absolute priority,' Dr Weill told AFP in an interview.
KAISERSLAUTERN, Germany – Two U.S. servicemembers based in Germany were suspected of being victims of Europe's E. coli outbreak Friday, as European authorities said the outbreak was "stabilizing."
U.S. military medical officers were awaiting test results from samples taken from the ill servicemembers -- and they could be confirmed late Friday or Monday, according to Phillip Tegtmeier, a spokesman for the US military's Europe Regional Medical Command.
"We're testing [for E. coli] as a precaution," he told military newspaper Stars and Stripes on Friday.
[Click title for full article]
BERLIN (AP) -- Germany's national disease control center says almost 200 new cases of E. coli infection were reported in the first two days of June, bringing the number of cases in the country to 1,733. Eighteen people have died, all but one in Germany.
The Robert Koch Institute said Friday that 520 of those sickened are suffering from a life-threatening complication that can cause kidney failure.
Suspicion has fallen on raw tomatoes, cucumbers and lettuce as the source of the germ but researchers have been unable to pinpoint the exact source.
The World Health Organization says nine other European nations have reported a total of 80 people sick from the bacteria, most of whom had recently visited northern Germany.
Thursday, June 2, 2011
Maria Cheng and Kirsten Grieshaber, Associated Press, On Thursday June 2, 2011, 7:04 pm
LONDON (AP) -- Scientists on Thursday blamed Europe's worst recorded food-poisoning outbreak on a "super-toxic" strain of E. coli bacteria that may be brand new.
But while suspicion has fallen on raw tomatoes, cucumbers and lettuce as the source of the germ, researchers have been unable to pinpoint the food responsible for the frightening illness, which has killed at least 18 people, sickened more than 1,600 and spread to least 10 European countries.
An alarmingly large number of victims -- about 500 -- have developed kidney complications that can be deadly.
Chinese and German scientists analyzed the DNA of the E. coli bacteria and determined that the outbreak was caused by "an entirely new, super-toxic" strain that contains several antibiotic-resistant genes, according to a statement from the Shenzhen, China-based laboratory BGI. It said the strain appeared to be a combination of two types of E. coli.
[click on title for full story]
German health officials struggling to find the source of deadly E.Coli outbreak suffered another setback when Spanish cucumbers were found to have been incorrectly declared the source of the infections; so far seventeen people have died and more than 1,500 Europeans have been sickened by a rare strain of enterohemorrhagic E. Coli (EHEC); eighty new cases were reported in Hamburg between Monday and Tuesday alone and hospitals are treating 110 patients critically ill with hemolytic uremic syndrome (HUS); the current outbreak has disproportionately affected women, and health officials are struggling to understand why; health officials have urged to not purchase any vegetables declared as potentially dangerous
[click on title for full article]
World Health Organisation says fatal E coli is a mutant blend of two different varieties and has never been seen before
Preliminary genetic sequencing suggests the strain is a mutant form of two different E coli bacteria, with lethal genes that could explain why the Europe-wide outbreak appeared to be so big and dangerous, the agency said.
Hilde Kruse, a food safety expert at the WHO, told the Associated Press that "this is a unique strain that has never been isolated from patients before".
She added that the new strain has "various characteristics that make it more virulent and toxin-producing".
So far the mutant E coli strain has infected more than 1,500, including 470 who have developed a rare kidney failure complication. Researchers have been unable to pinpoint the cause of the outbreak, which has hit at least nine European countries.
[Full article please click on title]
The source of the outbreak, which has killed at least 16 people — 15 in Germany and a Swede who visited there recently — remained unknown.
Scientists are at a loss to explain why this little-known organism, identified as E. coli 0104:H4, has proved so virulent.
[click title for full story]
The World Health Organization says the E. coli strain responsible for the deadly outbreak in Europe is a new bacteria that has never been seen before.
The agency says Thursday that preliminary genetic sequencing suggests the strain is a mutant form of two different E. coli bacterium, with lethal genes that could explain why the Europe-wide outbreak appears to be so massive and dangerous.
Hilde Kruse, a food safety expert at the World Health Organization, said "this is a unique strain that has never been isolated from patients before." She added that the new strain has "various characteristics that make it more virulent and toxin-producing."
Wednesday, June 1, 2011
Student BMJ editorial: Antimicrobials in livestock
Excessive use of antimicrobials in livestock promotes resistance and risks the future health of both animals and humans, warn experts in an editorial published by Student BMJ today.
Jørgen Schlundt and colleagues at the National Food Institute in Denmark argue that the routine use of antimicrobials can be reduced substantially, while maintaining profitable animal production, and call for their use to be monitored in all countries.
Antimicrobials are essential for treating bacterial infections in humans and animals. Substantial amounts are used in modern animal production, but their use can result in bacteria that are resistant to treatment.
Resistant bacteria can spread from animals to humans, mainly through the food chain.
Three of four recently emerging infections in humans originate from animals: avian influenza H5N1, severe acute respiratory syndrome (SARS), and Salmonella.
Several global organisations have proposed a range of different actions to contain antimicrobial resistance from animals, including restricting use in animals of the most critically important antimicrobials for humans. The European Union has also begun monitoring resistance in food animals and is implementing mandatory monitoring of antimicrobial usage in all member states...
Source: World Health Organisation (WHO), CSR, Disease Outbreak News
Avian influenza situation in Egypt -- WHO update 52
The Ministry of Health of Egypt has announced a new confirmed case of
human infection with avian influenza A (H5N1) virus.
The case is a 30-year-old female from Amria District, Alexandria
Governorate. She developed symptoms on 26 Apr 2011 and was
hospitalized on 3 May 2011. She was in a critical condition under
artificial ventilation and died on 9 May 2011. She had received
oseltamivir treatment at the time of hospitalization.
Investigations into the source of infection indicate that the patient
had exposure to sick poultry suspected to have avian influenza.
The case was confirmed by the Egyptian Central Public Health
Laboratory, a National Influenza Center of the WHO Global Influenza
Surveillance Network. Of the 144 cases confirmed to date in Egypt, 48
have been fatal.
ProMED-mail Rapporteur Marianne Hopp
[This brings the overall total of human cases of avian influenza
A/H5N1 virus infection since the beginning of the outbreak in 2003 to
554, and the number of fatalities to 324. There have now been 38 cases
of avian A/H5N1 influenza in 2011 and 18 fatalities.
During the 1st 5 months of 2011, 25 of the 38 new human cases (66
percent) have been recorded in Egypt, but only 8 of the 18 fatalities
A map of the governorates of Egypt can be accessed at
The Epidemic Detectives
By Veronika Hackenbroch, Samiha Shafy and Frank Thadeusz
The bacterium that is currently is an enterohemorrhagic strain of the bacterium Escherichia coli (EHEC), a close relative of harmless intestinal bacteria, but one that produces the dangerous...
The bug being blamed for the deaths and a swath of hospitalizations—many of which require intensive care and kidney dialysis—is among a group of toxin-producing E.coli called enterohemorrhagic E. coli, which can cause kidney failure and bloody diarrhea.
The northern German city of Hamburg has become the epicenter of the outbreak, which German officials initially blamed on shipments of Spanish cucumbers.
John Dalli, the European commissioner for Health and Consumer Policy, said that..
Lisa Schnirring Staff Writer
Jun 1, 2011 (CIDRAP News) – Health officials today reported two new H5N1 avian influenza cases, in an Egyptian woman who died from the disease and in an Indonesian toddler who is recovering.
Egypt's health ministry said the 30-year-old woman from Alexandria governorate got sick on Apr 26 and was hospitalized on May 3, where she was placed on a ventilator and received oseltamivir (Tamiflu), according to a report today from the World Health Organization (WHO). She died on May 9.
An investigation into the source of her illness revealed..
|English.news.cn 2011-06-01 13:37:20|
ANXI, Fujian, June 1 (Xinhua) -- More than 100 children in Fujian Province have been infected with viral encephalitis since the beginning of May, local health authorities said Wednesday.
Hospitals in Anxi County have reported 200 such cases since June 1, of which 115 have been confirmed, said Wu Zhengxin, director of the county's health bureau.
An investigation by experts from the Ministry of Health and local disease control centers has indicated that the outbreak was caused by the ECHO30-type intestinal virus, according to Wu.
Infected local children were being treated at Mingxuan Hospital of Anxi County and were in stable condition, Wu said.
Another nine children, also from Anxi County, were diagnosed in hospitals in Xiamen City of Fujian and were receiving treatment there, Wu added.
The children, all under the age of 12, are from 75 villages of 14 townships in the county.
Children of three to seven years old account for 78 percent of the total, and 117 children, or 65 percent, are from the town of Hutou.
Local heath authorities are closely monitoring the disease to prevent its further spread, Wu said
Monday, May 30, 2011
Dr. Adel Anwar, Undersecretary of the Department of Veterinary Medicine on Monday morning he was discovered 13 infected domestic focus of bird flu, and most of those spots thanked the city of Kafr Qalubia all in injuries in ducks and chickens.
He said: that there are no human cases of bird flu have been recorded one case of the Directorate during the last period.
Monday, May 30, 2011 - 13:11
Minister of Health. Ashraf Hatem
Dana wrote railway
In response to the report published by the "seventh day" yesterday for the emergence of 4 cases of plague city of Tobruk, Libya, which lies on the border with Egypt, stressed Dr. Naeema Deputy Regional Director of WHO, the organization began yesterday to investigate the health of the emergence of people with the plague in collaboration with the Center for Disease Control transition in Tripoli.
She added that this action is taken immediately after the announcement of the appearance of any cases of infectious disease to ensure the accuracy of the declaration, and non-infected to take preventive measures to prevent transmission, and for the possibility of transmission of Egypt, stressed that Egypt is one of the countries that have strict procedures to prevent the transmission of any diseases through its borders to the absence of any health problem on the Egyptian-Libyan border.
Menoufiya Mohammed Issawi 30-5-2011 13:55 28
Flu Taioraandzt Directorate of Health Affairs Menoufia housewife unique Shaaban Abdel-Latif, honor (21 years), from the estate Hamza village Alguenatrin Ashmoon within the hospital on suspicion of being infected with avian influenza and the emergence of symptoms of the disease was taking a sample of blood and sent to labs central Ministry of Health for analysis .
And Department of Veterinary Medicine announced the emergence of bifocal are positive for bird flu each house of Mohammed Sabir structure of the village of Mit Abu Sheikha Bakuesna, and on the mind of a spectrum of Quesna and the execution of 45 birds infected with the disease of houses and Ttherhma and take the procedures followed in this regard.
Sunday, May 29, 2011
Menoufiya - Fadel, Marwa
Menoufiya - Fadel, Marwa
Dr Ahmed Fuad, the director of Veterinary Medicine Menoufia, the emergence of a new, positive focus of avian influenza, the home of citizenship Hayam Recep Mahi shebin Kom tribal district as a result of education at home.
The "Fuad" to the fact that the focus has been discovered by field tests carried out by the Directorate, and turned out to be domestic breeding samples were taken from birds and sent to the central laboratory and the result is positive, explaining that he had been culling of infected and vaccinated birds nearby to prevent the spread of the disease.
47 Sunday, May 29, 2011 - 11:47
Recorded the Libyan city of Tobruk the emergence of several infectious disease, injuries plague, and a medical source said the city's central hospital, said that at least four cases have been isolated medical hospital.
He pointed out that there are 17 other case being the work of medical tests her on suspicion of being infected with the disease, said medical source, who preferred anonymity, that the state of panic and fear, which hit the city is not the first, which occurred before, in mid-June 2009, when it hit the Plague "14" state in the region Trcp on the outskirts of Tobruk, and resulted in deaths and one.
The source added that the Egyptian authorities to take necessary action on the Egyptian-Libyan border to prevent the transmission of the disease in Egypt.
An official quarantine alternate port Salloum, The fear of the spread of the disease in Egypt will be the biggest focus of the emergence of the former in 2009, and attributed to the Egyptian official lawlessness taking place in the Libyan-Egyptian border at the moment.
And suffer the border city of Tobruk, many difficulties in the field of health services, where it lost contact in the capital Tripoli since the outbreak of the revolution on February 17 last year.
German health chiefs announced four more deaths feared to have been caused by E. coli-contaminated cucumbers, bringing to ten the number of suspected deaths in the country.
Two of the ten deaths have so far been officially attributed to the deadly E. coli strain, with about 300 cases of infection reported in several countries in the past week
The four new deaths in north Germany were announced by the health ministry of Schleswig-Holstein state and a clinic in Hamburg. The victims were three women in their 80s and a fourth in her 30s.
Authorities in southern Spain said Saturday they had introduced restrictions on two distributors suspected of exporting cucumbers tainted with the bacteria that causes the potentially fatal haemolytic uraemic syndrome (HUS).
The regional council of Andalusia said suspect batches of cucumbers had been withdrawn pending laboratory checks whose results would be known Monday.
The European Commission said earlier that Spain had suspended the activities of two distributors in the southern provinces of Almeria and Malaga, but spokesman Frederic Vincent confirmed Saturday that only the greenhouses where the suspect cucumbers had been grown were affected.
We don't know where the contamination occurred, whether on the (Spanish) sites or along the distribution chain," he said.
A probe was launched and samples taken from the soil, water and products from the two agricultural sites, the European Union's executive arm said Friday.
The cucumbers are suspected to have been contaminated by the enterohaemorrhagic E. coli strain.
"Investigations are ongoing to identify other potential sources, while a third suspect batch of cucumbers originating either in the Netherlands or in Denmark, and traded in Germany, is also under investigation," it said.
A suspect consignment of Spanish cucumbers was distributed to Denmark, but authorities there traced the vegetables and withdrew them from the market, the statement said.
The Andalusian authorities said Saturday that exhaustive checks by the Malaga company on its cucumbers had shown them totally free of contamination.
"Nevertheless we decided to suspend the product as a preventive measure," a statement added.
In the other company, at Roquetas del Mar, a consignment had been identified with some difficulty, it said.
Samples from suspect batches had been sent to a laboratory in the northwest province of Galicia for testing.
Meanwhile the Spanish daily El Pais said the Malaga growers, Frunet Bio, had been advised from Germany four days after the dispatch of a consignment on May 12 that their cucumbers had been dropped on the ground in a Hamburg market.
"We have that in writing," it quoted a spokesman for Frunet Bio as saying Saturday. "When that happens we can no longer guarantee the product."
The Eppendorf clinic near Hamburg which recorded two of Saturday's deaths said it had introduced a new treatment with an antibody aimed at countering kidney damage, but would not know for several weeks if it worked.
Germany has confirmed 276 cases of HUS, by far the largest number in Europe.
Sweden has reported 25 E. coli cases, with 10 of those people developing HUS, according to the European Commission said. Denmark reported seven E. coli cases (including three HUS) while Britain counted three cases (two HUS).
The Netherlands had one HUS case and Austria reported two cases of enterohaemorrhagic E. coli, while Switzerland has one suspected case.
The French economy, health and agriculture ministries said Saturday that three suspected cases were being investigated in France, linked to the German epidemic and not to a batch of cucumbers withdrawn from sale earlier.
|Sunday, May 29, 2011|
After hurried action on controlling antibiotic resistance in response to the British study in superbug, Indian health authorities have questioned the study published in The Lancet Infectious Diseases which reported presence of NDM-1 superbug in water samples in Delhi.
The British paper has little "scientific evidence", Indian officials led by Director General of Health Services R K Srivastava have claimed in an editorial published in Indian Journal of Medical Research, brought out by the Indian Council of Medical Research (ICMR).
In the wake of the study which found the gene, known as New Delhi metallo-beta-lactamase or NDM-1 which makes bugs resistant to almost all antibiotics, in water samples in Delhi, the government hurriedly announced the long-pending antibiotic policy.
The study had warned that there was a threat of spread of this gene around the world and advised people against travelling to India for medical treatment.
The officials have argued that multi drug-resistant pathogens exist globally including the Western world with a death toll of over 2,500 in the US alone and some 2,500 deaths in Europe every year.
"Does it mean that the whole of Europe is unsafe for medical treatment and that all such notorious pathogens originated in Europe?" The editorial says "the (British) authors themselves admit that there was no statistically significant strain relatedness between the Indian 'British research biased against us' and UK isolates which raises doubts about the alleged origin of so-called NDM-1 from India. Mere fact that some of the study patients, shown to possess NDM-1, had visited India for some kind of surgery during preceding years is not adequate proof to claim the huge link with India. The authors could link only 17 of 37 UK patients to the Indian subcontinent.
Since no prescreening of the patients was done before their visit to India, it would be wrong to conclude that the 'bug' had its origin in India". "Even while the authors have admitted that there was no statistical proof of strain relatedness between Indian and the UK isolates, the Journal chose to publish the paper cautioning global community to refrain from undergoing surgery in India. The concluding remarks of the authors are biased ( against India)," the editorial says.