Friday, January 27, 2012

Indo: Study on Oseltamivir [Tamiflu] Resistance after Death of 5 yo in Jakarta #H5N1 #Birdflu

January 27, 2012

This study against the backdrop of the alleged drug Oseltamivir resistance after the death of a child aged five years at Friendship Hospital due to bird flu infected.

Ministry of Health is conducting a study to examine whether or not there has been resistance to oseltamivir, which has been a mainstay of Indonesia in handling bird flu patients.

"It takes time indeed. To meguji resistance needed a tool that was very expensive, but we hope this year can be known means," said the head of Research and Development of the Ministry of Health, Trihono, in Jakarta, today.

Upon completion of the study will get what is concrete evidence of oseltamivir resistance has occurred.

Previously alleged drug Oseltamivir resistance after the death of a child aged five years in the Friendship Hospital due to bird flu infected.

From the first day of fever, the child had been given oseltamivir. But his condition continued to decline rapidly until she died.

Yet according to the Director General of Disease Control and Environmental Health Kemenkes, Tjandra Yoga Aditama, patients who were given oseltamivir within 48 hours of the first since the symptoms of bird flu emerged, the chances for recovery are very large.

Trihono said that drug resistance could be due to the previous dose given was too small.

"Can we overcome by the addition of dose or combination with other drugs," he said.

Trihono said, if oseltamivir resistance does occur, its impact can be very troublesome because Indonesia is very dependent on the type of drug.

Currently Indonesia has 1.4 million doses of Oseltamivir are partly derived from other state grants.

"We're really praying and hoping, not to the resistance that we worry about it come true, because it means we have to change all the drug-related policies," he said.

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